Amlodipine Drug

An Amlodipine Drug is a Dihydropyridine Calcium Channel Blocker.

• Context:
  • It can be used to treat high blood pressure and coronary artery disease.
  • It can (often) be a Vasodilator (for vasodilation) by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle.
  • It can be administered orally.
  • It can have side effects including edema, fatigue, abdominal pain, and nausea.
  • It can be contraindicated in individuals with severe hypotension, aortic stenosis, or heart failure.
  • It can interact with other drugs such as simvastatin, increasing the risk of side effects.
  • ...
• Example(s):
  • Norvasc,
  • Istin,
  • Norliqva,
  • …
• Counter-Example(s):
  • Benidipine,
  • Cilnidipine,
  • Efonidipine.
• See: Calcium Channel Blocker, Calcium Channel Opener, Hypertension, Heart Arrhythmia, Antihypertensive Drug, High Blood Pressure, Ion Channel Blocker, Beta Blocker, Alpha Blocker, Phenylalkylamine Calcium Channel Blocker, Benzothiazepine Calcium Channel Blocker .

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References

2022

• (Wikipedia, 2022) ⇒ https://en.wikipedia.org/wiki/Amlodipine Retrieved:2022-12-8.
  • Amlodipine, sold under the brand name Norvasc among others, is a calcium channel blocker medication used to treat high blood pressure and coronary artery disease. It is taken by mouth.

    Common side effects include swelling, feeling tired, abdominal pain, and nausea. Serious side effects may include low blood pressure or heart attack. Whether use is safe during pregnancy or breastfeeding is unclear. When used by people with liver problems, and in elderly individuals, doses should be reduced. Amlodipine works partly by increasing the size of arteries. It is a long-acting calcium channel blocker of the dihydropyridine type.

    Amlodipine was patented in 1982, and approved for medical use in 1990. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the fifth most commonly prescribed medication in the United States, with more than 69million prescriptions.

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