Klebsiella Pneumoniae Bacteria

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Klebsiella Pneumoniae Bacteria is a Klebsiella bacteria (gram-negative, facultative anaerobic, rod-shaped, non-motile bacterium) that can infect the human respiratory tract and cause Pneumonia.



References

2018

  • (Wikipedia, 2018) ⇒ https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Retrieved:2018-8-18.
    • Klebsiella pneumoniae is a Gram-negative, non-motile, encapsulated, lactose-fermenting, facultative anaerobic, rod-shaped bacterium. It appears as a mucoid lactose fermenter on MacConkey agar.

      Although found in the normal flora of the mouth, skin, and intestines (Ryan, Ray and Sherris, 2004), it can cause destructive changes to human and animal lungs if aspirated (inhaled), specifically to the alveoli (in the lungs) resulting in bloody sputum. In the clinical setting, it is the most significant member of the Klebsiella genus of the Enterobacteriaceae. K. oxytoca and K. rhinoscleromatis have also been demonstrated in human clinical specimens. In recent years, Klebsiella species have become important pathogens in nosocomial infections.

      It naturally occurs in the soil, and about 30% of strains can fix nitrogen in anaerobic conditions (Postgate 1998). As a free-living diazotroph, its nitrogen-fixation system has been much-studied, and is of agricultural interest, as K. pneumoniae has been demonstrated to increase crop yields in agricultural conditions. Members of the genus Klebsiella typically express two types of antigens on their cell surfaces. The first, O antigen, is a component of the lipopolysaccharide (LPS), of which 9 varieties exist. The second is K antigen, a capsular polysaccharide with more than 80 varieties. Both contribute to pathogenicity and form the basis for serogrouping.

      It is closely related to K. oxytoca from which it is distinguished by being indole-negative and by its ability to grow on melezitose but not 3-hydroxybutyrate.


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