Pharmacokinetic Area Under the Curve (AUC) Measure
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An Pharmacokinetic Area Under the Curve (AUC) Measure is a Pharmacokinetic measure based on the definite integral of the concentration of a drug in blood plasma as a function of time.
- Context:
- It can reflect the actual body exposure to drug after administration of a dose of the drug.
- It can be expressed in mg*h/L.
- …
- See: Trapezoidal Rule, Pharmacokinetics, Definite Integral, AUC Classifier Measure, Blood Plasma, Liquid Chromatography–Mass Spectrometry.
References
2022
- (Wikipedia, 2022) ⇒ https://en.wikipedia.org/wiki/Area_under_the_curve_(pharmacokinetics) Retrieved:2022-8-26.
- In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral of the concentration of a drug in blood plasma as a function of time (this can be done using liquid chromatography–mass spectrometry[1] ). In practice, the drug concentration is measured at certain discrete points in time and the trapezoidal rule is used to estimate AUC.
- ↑ Cite error: Invalid
<ref>tag; no text was provided for refs namedMaurer 2005 pp. 310–318