Cohort Clinical Study

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A Cohort Clinical Study is an Observational Clinical Study that is a Cohort-based Study in which risk measures are assessed, and the cohort is monitored for a long time period (i.e. years).



References

2022

2021a

  • (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Cohort_study Retrieved:2021-11-21.
    • A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing a cross-section at intervals through time. It is a type of panel study where the individuals in the panel share a common characteristic.

      Cohort studies represent one of the fundamental designs of epidemiology which are used in research in the fields of medicine, nursing, psychology, social science, and in any field reliant on 'difficult to reach' answers that are based on evidence (statistics). In medicine for instance, while clinical trials are used primarily for assessing the safety of newly developed pharmaceuticals before they are approved for sale, epidemiological analysis on how risk factors affect the incidence of diseases is often used to identify the causes of diseases in the first place, and to help provide pre-clinical justification for the plausibility of protective factors (treatments).

2021b

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2005

  • (Everitt & Howell, 2005) ⇒ Brian S. Everitt, and D. Howell. (2005). “Encyclopedia of Statistics in Behavioral Science." Wiley. ISBN:9780470860809
    • QUOTE: In a controlled observational cohort study, two groups of subjects are selected from two populations that (hopefully) differ in only one characteristic at the start. The groups of subjects are studied for a specific period and contrasted at the end of the study period. For instance, smokers and nonsmokers are studied for a period of 10 years, and at the end the proportions of smokers and nonsmokers that died in that period are compared. On the other hand, in an intervention study, the subjects are selected from one population with a particular characteristic present; then, immediately after baseline, the total study group is split up into a group that receives the intervention and a group that does not receive that intervention (control group). The comparison of the outcomes of the two groups at the end of the study period is an evaluation of the intervention. For instance, smokers can be divided into those who will be subject to a smoking-cessation program and those who will not be motivated to stop smoking.[1]