Diazepam Drug
A Diazepam Drug is a benzodiazepine drug that acts as an anxiolytic.
- AKA: Valium.
- Context:
- It is used to treat anxiety, muscle spasms, seizures, alcohol withdrawal symptoms, and more.
- It enhances the effects of a natural chemical in the human body called gamma-aminobutyric acid (GABA). This helps to reduce the activity of particular brain's nerve cells, producing a calming effect.
- Example(s):
- Counter-Example(s):
- See: CYP2B6, Desmethyldiazepam, CYP2C19, CYP3A4, Cathine, Selective Serotonin Reuptake Inhibitor (SSRI), Anticonvulsant.
References
2023
- (ChatGPT-OpenAI, 2023) ⇒ https://chat.openai.com/chat Retrieved: 2023-03-12.
- Question: What is Diazepam?
Answer: Diazepam is a medication that belongs to the class of drugs known as benzodiazepines. It is commonly sold under the brand name Valium and is used to treat a variety of conditions, including anxiety, muscle spasms, seizures, and alcohol withdrawal symptoms. Diazepam works by enhancing the effects of a natural chemical in the body called gamma-aminobutyric acid (GABA), which helps to reduce the activity of certain nerve cells in the brain. This results in a calming effect on the body and mind, which can help to relieve symptoms of anxiety, muscle tension, and seizures. Diazepam can be taken orally in the form of tablets or capsules, and it is available by prescription only.
- Question: What is Diazepam?
2022
- (Wikipedia, 2022) ⇒ https://en.wikipedia.org/wiki/diazepam Retrieved:2022-11-28.
- Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is commonly used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. It may also be used to cause memory loss during certain medical procedures.[1] It can be taken by mouth, inserted into the rectum, injected into muscle, injected into a vein or used as a nasal spray. When given into a vein, effects begin in one to five minutes and last up to an hour. By mouth, effects begin after 15 to 60 minutes.
Common side-effects include sleepiness and trouble with coordination.[2] Serious side effects are rare. They include increased risk of suicide, decreased breathing, and an increased risk of seizures if used too frequently in those with epilepsy. Occasionally, excitement or agitation may occur.[3] Long-term use can result in tolerance, dependence, and withdrawal symptoms on dose reduction. Abrupt stopping after long-term use can be potentially dangerous. After stopping, cognitive problems may persist for six months or longer.[3] It is not recommended during pregnancy or breastfeeding. Its mechanism of action works by increasing the effect of the neurotransmitter gamma-aminobutyric acid (GABA).[3]
Diazepam was patented in 1959 by Hoffmann-La Roche. It has been one of the most frequently prescribed medications in the world since its launch in 1963. In the United States it was the best-selling medication between 1968 and 1982, selling more than 2billion tablets in 1978 alone. In 2020, it was the 128th most-commonly prescribed medication in the United States, with more than 4million prescriptions. In 1985 the patent ended, and there are now more than 500 brands available on the market. It is on the World Health Organization's List of Essential Medicines.
- Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is commonly used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. It may also be used to cause memory loss during certain medical procedures.[1] It can be taken by mouth, inserted into the rectum, injected into muscle, injected into a vein or used as a nasal spray. When given into a vein, effects begin in one to five minutes and last up to an hour. By mouth, effects begin after 15 to 60 minutes.
- ↑ "Diazepam". PubChem. National Institute of Health: National Library of Medicine. 2006. Archived from the original on 30 June 2015. Retrieved 11 March 2006.
- ↑ "Valium – diazepam tablet". DailyMed. 8 November 2019. Retrieved 30 December 2019.
- ↑ 3.0 3.1 3.2 Riss J, Cloyd J, Gates J, Collins S (August 2008). "Benzodiazepines in epilepsy: pharmacology and pharmacokinetics". Acta Neurologica Scandinavica. 118 (2): 69–86. doi:10.1111/j.1600-0404.2008.01004.x. PMID 18384456. S2CID 24453988.