Bile Acid Biosynthesis Process

A Bile Acid Biosynthesis Process is a hepatic catabolic lipid conversion process.

• AKA: Bile Acid Synthesis Pathway, Cholesterol 7α-Hydroxylation Pathway, Bile Salt Formation Process.
• Context:
  • It can typically eliminate Cholesterol Molecules through bile acid biosynthesis conversion.
  • It can typically produce Primary Bile Acids via bile acid biosynthesis enzymatic cascade.
  • It can typically require Cytochrome P450 Enzymes for bile acid biosynthesis hydroxylation.
  • It can typically occur in Hepatocytes as bile acid biosynthesis exclusive location.
  • It can typically involve Multiple Hydroxylation Steps in bile acid biosynthesis pathway.
  • ...
  • It can often regulate Cholesterol Homeostasis through bile acid biosynthesis elimination route.
  • It can often respond to FXR Nuclear Receptors via bile acid biosynthesis feedback control.
  • It can often produce Cholic Acid and bile acid biosynthesis chenodeoxycholic acid.
  • It can often support Fat Digestion through bile acid biosynthesis emulsification product.
  • ...
  • It can range from being a Classical Bile Acid Biosynthesis Process to being an Alternative Bile Acid Biosynthesis Process, depending on its bile acid biosynthesis enzymatic route.
  • It can range from being a Basal Bile Acid Biosynthesis Process to being an Induced Bile Acid Biosynthesis Process, depending on its bile acid biosynthesis regulatory state.
  • ...
  • It can utilize CYP7A1 Enzymes as bile acid biosynthesis rate-limiting enzyme.
  • It can connect to Cholesterol Biosynthesis Processes through bile acid biosynthesis substrate utilization.
  • It can interface with Enterohepatic Circulations via bile acid biosynthesis product recycling.
  • It can support Detoxification Processes through bile acid biosynthesis xenobiotic elimination.
  • It can interact with Gut Microbiomes via bile acid biosynthesis secondary conversion.
  • ...
• Example(s):
  • Bile Acid Biosynthesis Process Pathways, such as:
    • Classical Bile Acid Biosynthesis Processes, such as:
      • CYP7A1-Initiated Bile Acid Biosynthesis Process via bile acid biosynthesis neutral pathway.
      • 12α-Hydroxylated Bile Acid Biosynthesis Process producing bile acid biosynthesis cholic acid.
    • Alternative Bile Acid Biosynthesis Processes, such as:
      • CYP27A1-Initiated Bile Acid Biosynthesis Process through bile acid biosynthesis acidic pathway.
      • Oxysterol-Based Bile Acid Biosynthesis Process in bile acid biosynthesis extrahepatic tissues.
  • Bile Acid Biosynthesis Process States, such as:
    • Cholestatic Bile Acid Biosynthesis Process in bile acid biosynthesis disease condition.
    • Upregulated Bile Acid Biosynthesis Process with bile acid biosynthesis cholesterol lowering.
  • ...
• Counter-Example(s):
  • Steroid Hormone Biosynthesis Processes, which produce hormone molecules rather than bile acid molecules.
  • Bile Acid Conjugation Processes, which modify rather than synthesize bile acid structures.
  • Cholesterol Esterification Processes, which store rather than eliminate cholesterol molecules.
• See: Hepatic Metabolic Process, Cholesterol Metabolism, CYP7A1 Enzyme, FXR Nuclear Receptor, Detoxification Process, Enterohepatic Circulation.

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