Case-Control Clinical Study

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A Case-Control Clinical Study is an observational clinical trial in which two existing experimental unit groups differing in observed outcome are identified and compared on the basis of some supposed causal attribute.



References

2022

2021a

  • (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Case–control_study Retrieved:2021-11-21.
    • A case–control study (also known as case–referent study) is a type of observational study in which two existing groups differing in outcome are identified and compared on the basis of some supposed causal attribute. Case–control studies are often used to identify factors that may contribute to a medical condition by comparing subjects who have that condition/disease (the "cases") with patients who do not have the condition/disease but are otherwise similar (the "controls").[1] They require fewer resources but provide less evidence for causal inference than a randomized controlled trial. A case–control study produces only an odds ratio, which is an inferior measure of strength of association compared to relative risk.

2021b

  • (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Glossary_of_clinical_research Retrieved:2021-11-21.
    • Case-control study
      • A study that compares two groups of people: those with the disease or condition under study (cases) and a very similar group of people who do not have the disease or condition (controls). Researchers study the medical and lifestyle histories of the people in each group to learn what factors may be associated with the disease or condition. For example, one group may have been exposed to a particular substance that the other was not. Also called a retrospective study. (NCI)

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