Clinical Outcome Assessment (COA) Scoring System

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A Clinical Outcome Assessment (COA) Scoring System is an measurement system that can solve a COA scoring task (to convert a completed COA into a COA score).



References

2021

  • (Duong et al., 2021) ⇒ Tina Duong, Kristin J. Krosschell, Meredith K. James, Leslie Nelson, Lindsay N. Alfano, Katy Eichinger, Elena Mazzone et al. (2021). “Consensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases.” Frontiers in genetics 12
    • QUOTE: ... Critical components of successful evaluation of clinical outcome assessments (COAs) in multisite clinical trials and clinical practice are standardized training, administration, and documented reliability of scoring. Experiences of evaluators, alongside patient differences from regional standards of care, may contribute to heterogeneity in clinical center’s expertise. Achieving low variability and high reliability of COA is fundamental to clinical research and to give confidence in our ability to draw rational, interpretable conclusions from the data collected. ...

      ... Studies show that clinical experience is only one variable in accuracy and improved scoring of COAs. The most significant factor in improved accuracy in scoring COAs is CE foundational knowledge, familiarity with patients in NMD and frequency of training sessions. Targum (2006) found that with at least one training session, CEs of all clinical experience levels improved, but those who participated in 5 or more training sessions performed significantly better than those who attended only 1 session. ...

      ... However, our experiences and recommendations align with published studies in behavioral and neurological research on the importance and need for centralized, standardized training to ensure reliable administration and scoring of COAs (Kobak et al., 2004; Targum, 2006; Jeglic et al., 2007; Walker et al., 2014). ...