Diphenhydramine

A Diphenhydramine is an Antihistamine that blocks the action of histamine.

• Context:
  • It can be used to treat allergy symptoms, motion sickness, and insomnia.
  • It can be used as a mild sedative.
  • It can be used in combination with other medications to treat flu and cold.
  • It can have the following common side effects: drowsiness, dizziness, dry mouth, blurred vision, and constipation.
  • It is among the most commonly misused over-the-counter drugs in the United States.
  • …
• Example(s):
  • Benadryl,
  • Nytol,
  • Sominex,
  • ZzzQuil,
  • Unisom,
  • Tylenol PM,
  • …
• Counter-Example(s):
  • Acetaminophen,
  • Cetirizine,
  • Guaifenesin,
  • Ibuprofen,
  • Loratadine,
  • Phenylephrine,
  • Pseudoephedrine.
• See: Oral Administration, Intramuscular Injection, Intravenous Therapy, Topical Medication, Rectal Administration, Liver, CYP2D6, Hour, Urine, Feces.

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References

2023

• (ChatGPT-OpenAI, 2023) ⇒ https://chat.openai.com/chat Retrieved:2023-3-12.
  • Q: what is Diphenhydramine?

    A: Diphenhydramine is a first-generation antihistamine medication that is commonly used to treat symptoms of allergies, such as itching, sneezing, runny nose, and hives. It works by blocking the action of histamine, a chemical that is released in response to allergens, and is responsible for causing allergy symptoms.

    Diphenhydramine can also be used to treat symptoms of motion sickness, insomnia, and as a mild sedative. It is available in various forms, including tablets, capsules, and syrups. In some cases, it may also be used in combination with other medications to treat certain conditions, such as colds and flu. It is important to follow the instructions provided by your healthcare provider or on the medication label when using diphenhydramine to ensure its safe and effective use.

  • Q:What are the side effects of Diphenhydramine?

    Diphenhydramine can cause a variety of side effects, some of which may be serious. Common side effects include drowsiness, dizziness, dry mouth, blurred vision, and constipation. Other less common side effects include:

    • Nausea and vomiting
    • Difficulty urinating
    • Confusion and agitation
    • Restlessness and excitability
    • Headache
    • Thickening of bronchial secretions
    • Sweating
    • Skin rash
  • In rare cases, diphenhydramine can cause more serious side effects, such as:
    • Anaphylaxis, a severe allergic reaction that can be life-threatening
    • Seizures
    • Irregular heartbeat
    • Severe dizziness or fainting

2022

• (Wikipedia, 2022) ⇒ https://en.wikipedia.org/wiki/diphenhydramine Retrieved:2022-10-23.
  • Diphenhydramine (DPH) is an antihistamine medication mainly used to treat allergies. It can also be used for insomnia, symptoms of the common cold, tremor in parkinsonism, and nausea. It is taken by mouth, injected into a vein, injected into a muscle, or applied to the skin. Maximal effect is typically around two hours after a dose, and effects can last for up to seven hours.

    Common side effects include sleepiness, poor coordination and an upset stomach. Its use is not recommended in young children or the elderly. There is no clear risk of harm when used during pregnancy; however, use during breastfeeding is not recommended. It is a first generation H₁-antihistamine and ethanolamine and works by blocking certain effects of histamine. Diphenhydramine is also a potent anticholinergic, and works as a deliriant at higher than recommended doses as a result. This has led to some cases of recreational use and addiction. Diphenhydramine was first made by George Rieveschl and came into commercial use in 1946. It is available as a generic medication. It is sold under the brand name Benadryl, among others. In 2017, it was the 241st most commonly prescribed medication in the United States, with more than two million prescriptions.

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