Epigenome

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An Epigenome is a chemical compound set that can tell the genome what to do.



References

2022

  • (Wikipedia, 2022) ⇒ https://en.wikipedia.org/wiki/epigenome Retrieved:2022-1-7.
    • An epigenome consists of a record of the chemical changes to the DNA and histone proteins of an organism; these changes can be passed down to an organism's offspring via transgenerational stranded epigenetic inheritance. Changes to the epigenome can result in changes to the structure of chromatin and changes to the function of the genome.[1]

      The epigenome is involved in regulating gene expression, development, tissue differentiation, and suppression of transposable elements. Unlike the underlying genome, which remains largely static within an individual, the epigenome can be dynamically altered by environmental conditions.

2021

  • https://www.genome.gov/about-genomics/fact-sheets/Epigenomics-Fact-Sheet
    • QUOTE: ... The epigenome is a multitude of chemical compounds that can tell the genome what to do. The human genomeis the complete assembly of DNA (deoxyribonucleic acid)-about 3 billion base pairs - that makes each individual unique. DNA holds the instructions for building the proteins that carry out a variety of functions in a cell. The epigenome is made up of chemical compounds and proteins that can attach to DNA and direct such actions as turning genes on or off, controlling the production of proteins in particular cells. When epigenomic compounds attach to DNA and modify its function, they are said to have "marked" the genome. These marks do not change the sequence of the DNA. Rather, they change the way cells use the DNA's instructions. The marks are sometimes passed on from cell to cell as cells divide. They also can be passed down from one generation to the next. ...