Mitochondrial Myopathy
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A Mitochondrial Myopathy is a Myopathy associated with a mitochondrial disease.
- See: Non-Mendelian Inheritance#Extranuclear Inheritance, Myopathy, Mitochondrial Disease, Succinate Dehydrogenase, Cytochrome c Oxidase.
References
2021
- (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Mitochondrial_myopathy Retrieved:2021-11-2.
- Mitochondrial myopathies are types of myopathies associated with mitochondrial disease. On biopsy, the muscle tissue of patients with these diseases usually demonstrate "ragged red" muscle fibers. These ragged-red fibers contain mild accumulations of glycogen and neutral lipids, and may show an increased reactivity for succinate dehydrogenase and a decreased reactivity for cytochrome c oxidase. Inheritance was believed to be maternal (non-Mendelian extranuclear). It is now known that certain nuclear DNA deletions can also cause mitochondrial myopathy such as the OPA1 gene deletion. There are several subcategories of mitochondrial myopathies.