Progression-Free Survival (PFS)

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A Progression-Free Survival (PFS) is an healthcare measure based on the length of time during and after the treatment of a disease, such as cancer, that a patient lives with the disease but it does not get worse.



References

2022

  • (Wikipedia, 2022) ⇒ https://en.wikipedia.org/wiki/Progression-free_survival Retrieved:2022-2-10.
    • Progression-free survival (PFS) is "the length of time during and after the treatment of a disease, such as cancer, that a patient lives with the disease but it does not get worse". In oncology, PFS usually refers to situations in which a tumor is present, as demonstrated by laboratory testing, radiologic testing, or clinically. Similarly, "disease-free survival" is the length of time after patients have received treatment and have no detectable disease. Time to progression (TTP) does not count patients who die from other causes but is otherwise a close equivalent to PFS (unless there are many such events). The FDA gives separate definitions and prefers PFS.

2021

  • (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Clinical_endpoint#Scope Retrieved:2021-11-15.
    • … A clinical trial will usually define or specify a primary endpoint as a measure that will be considered success of the therapy being trialled (e.g. in justifying a marketing approval). The primary endpoint might be a statistically significant improvement in overall survival (OS). A trial might also define one or more secondary endpoints such as progression-free-survival (PFS) that will be measured and are expected to be met. A trial might also define exploratory endpoints that are less likely to be met. ...

2021

2020