Reuptake Inhibitor (RI)
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A Reuptake Inhibitor (RI) is a Reuptake Modulator that ...
- Example(s):
- an Norepinephrine-Dopamine Reuptake Inhibitor (NDRI) (of dopamine and norepinephrine), such as: ...
- a Selective Serotonin Reuptake Inhibitor (SSRI) (of serotonin), such as: ...
- …
- See: Endocannabinoid, Talk:Reuptake Inhibitor, Reuptake Modulator, Plasmalemma, Neurotransmitter Transporter, Reuptake, Neurotransmitter, Synapse, Extracellular, Concentration, Neurotransmission, Drug.
References
2022
- (Wikipedia, 2022) ⇒ https://en.wikipedia.org/wiki/Reuptake_inhibitor Retrieved:2022-11-22.
- A reuptake inhibitor (RI) is a type of drug known as a reuptake modulator that inhibits the plasmalemmal transporter-mediated reuptake of a neurotransmitter from the synapse into the pre-synaptic neuron. This leads to an increase in extracellular concentrations of the neurotransmitter and an increase in neurotransmission. Various drugs exert their psychological and physiological effects through reuptake inhibition, including many antidepressants and psychostimulants.
Most known reuptake inhibitors affect the monoamine neurotransmitters serotonin, norepinephrine (and epinephrine), and dopamine.[1] However, there are also a number of pharmaceuticals and research chemicals that act as reuptake inhibitors for other neurotransmitters such as glutamate, γ-aminobutyric acid (GABA), glycine, adenosine, choline (the precursor of acetylcholine), and the endocannabinoids, among others.[1]
- A reuptake inhibitor (RI) is a type of drug known as a reuptake modulator that inhibits the plasmalemmal transporter-mediated reuptake of a neurotransmitter from the synapse into the pre-synaptic neuron. This leads to an increase in extracellular concentrations of the neurotransmitter and an increase in neurotransmission. Various drugs exert their psychological and physiological effects through reuptake inhibition, including many antidepressants and psychostimulants.