Therapeautic Drug

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A Therapeautic Drug is a pharmacological treatment/drug that is a therapeutic.



References

2021

  • https://www.ema.europa.eu/en/glossary/medicinal-product
    • QUOTE: ... A substance or combination of substances that is intended to treat, prevent or diagnose a disease, or to restore, correct or modify physiological functions by exerting a pharmacological, immunological or metabolic action. ...

2021

2021

  • (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Medication#Definition Retrieved:2021-10-25.
    • In Europe, the term is "medicinal product", and it is defined by EU law as:
      • "Any substance or combination of substances presented as having properties for treating or preventing disease in human beings; or"
      • "Any substance or combination of substances which may be used in or administered to human beings either with a view to restoring, correcting or modifying physiological functions by exerting a pharmacological, immunological or metabolic action, or to making a medical diagnosis."[1]Template:Rp
    • In the US, a "drug" is:
      • A substance recognized by an official pharmacopeia or formulary.
      • A substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease.
      • A substance (other than food) intended to affect the structure or any function of the body.
      • A substance intended for use as a component of a medicine but not a device or a component, part or accessory of a device.
      • Biological products are included within this definition and are generally covered by the same laws and regulations, but differences exist regarding their manufacturing processes (chemical process versus biological process).

2021

2021

Rank Drug Main indication Trade name 2015 2016 2017 2018 2019
1 adalimumab rheumatoid arthritis Humira 10.1 13.5 16.3 18.4 21.4
2 apixaban anticoagulant Eliquis 1.6 3.0 4.6 7.1 9.9
3 etanercept rheumatoid arthritis Enbrel 7.2 7.6 7.9 8.0 8.1
4 ustekinumab psoriasis Stelara 2.0 2.6 3.7 5.0 6.6
5 pembrolizumab oncology Keytruda 0.4 0.7 2.2 4.3 6.5

2020

  • https://pharmaintelligence.informa.com/resources/product-content/pharma-randd-annual-review-2021
    • QUOTE: ... Table 2 breaks down these solar systems of therapeutic areas into the individual planets of the 240 therapeutic categories. For the third year in a row, the Anticancer, immunological category sits at the summit, with another sizeable increase in its gravitational pull, with 8.1% more drugs in its pipeline than a year ago. Again, the rate of expansion has slowed compared to the previous year. The other more general anticancer category – Anticancer, other – sticks at number two, put we can see that the hyperdrive of immuno-oncology is causing the leading category to put further space between the top two. At three, there’s a further sizeable regeneration of the gene therapy franchise, of which more in a moment. The highest climber is, unsurprisingly, the general antiviral category, which leaps up from number 28 into the top five, with a supermassive 126% increase in its drug count. Just behind it are anti-infective prophylactic vaccines. ...
Table 2: Top 25 Therapeutic Categories
Position 2021 (2020)	Therapy	No of active compounds 2021 (2020)
1 (1)	Anticancer, immunological	3,712 (3,434)
2 (2)	Anticancer, other	2,680 (2,510)
3 (3)	Gene therapy	1,589 (1,273)
4 (4)	Monoclonal antibody, other	1,136 (1,009)
5 (28)	Antiviral, other	858 (380)
6 (6)	Prophylactic vaccine, anti-infective	843 (698)
7 (5)	Ophthalmological, other	781 (756)
8 (7)	Neurological	781 (666)
9 (10)	Anti-inflammatory	639 (529)
10 (14)	Cellular therapy, chimaeric antigen receptor	612 (491)
11 (8)	Antidiabetic	569 (589)
12 (11)	Monoclonal antibody, humanized	555 (508)
13 (9)	Immunosuppressant	542 (544)
14 (12)	Musculoskeletal	521 (504)
15 (18)	Monoclonal antibody, human	494 (448)
16 (15)	GI inflammatory/bowel disorders	482 (488)
17 (13)	Reformulation, other	470 (492)
18 (17)	Cognition enhancer	459 (466)
19 (23)	Hepatoprotective	453 (418)
20 (35)	Respiratory	446 (303)
21 (16)	Cardiovascular	444 (468)
22 (27)	Cellular therapy, stem cell	428 (391)
23 (19)	Analgesic, other	427 (448)
24 (21)	Neuroprotective	426 (421)
25 (30)	Cellular therapy, other	419 (350) 

  1. Directive 2004/27/EC Official Journal of the European Union. 30 April 2004 L136
  2. https://www.medthority.com database of prescription pharmaceutical products including drug classifications https://www.medthority.com/drugs/