Work Productivity and Activity Impairment (WPAI) Questionnaire
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A Work Productivity and Activity Impairment (WPAI) Questionnaire is a PRO assessment that is a self-administered questionnaire designed to measure how work productivity and activities are impaired by a specific health condition or disease.
- AKA: Work Productivity and Activity Impairment (WPAI) Measure, Work Productivity and Activity Impairment (WPAI) Instrument.
- Example(s):
- Counter-Example(s):
- See: Clinical Outcome Assessment (COA) Instrument, Interventional Clinical Trial, Observational Clinical Trial, Medical Treatment, SAFER Eligibility Check, Patient Intervention Questionnaire, Patient Intervention Outcome, Electronic Clinical Outcome Assessment (eCOA) System, Electronic Patient-Reported Outcome (ePRO).
References
2021
- (Gong & Li, 2021) ⇒ L. Gong, and C. Li (2021). "AB0927-Pare Work Productivity And Activity Impairment In Patients With SAPHO Syndrome". In: Annals of the Rheumatic Diseases 2021;80:1484-1485.
- QUOTE: The purpose of this study is to give an overview of work productivity loss in SAPHO patients through the work productivity and activity impairment (WPAI) questionnaire and investigate the relationship between the WPAI and other disease-related indicators.
2018
- (Yarlas et al., 2018) ⇒ Aaron Yarlas, Stephen M. Maher, Martha S. Bayliss, Andrew Lovley, Joseph C. Cappelleri, and Marco D. DiBonaventura (2018). "Psychometric validation of the work productivity and activity impairment questionnaire in ulcerative colitis: results from a systematic literature review". In: Journal of patient-reported outcomes, 2(1), 1-12.
- QUOTE: Patients with ulcerative colitis, a type of inflammatory bowel disease, report negative impacts of disease symptoms on work-related outcomes, including absenteeism and presenteeism. As a way to better understand the impact of this disease and its treatment on work-related outcomes, the current review examines the use of the Work Productivity and Activity Impairment Questionnaire (WPAI), a patient-reported outcomes measure of absenteeism, presenteeism, and impairment in other activities, in studies of patients with ulcerative colitis. This review assesses the measurement properties of the WPAI in this patient population: its reliability, construct validity, ability to detect change, and responsiveness to effective treatments (...)
2012a
- (Reilly et al., 2012) ⇒ Margaret C. Reilly, Ann Tanner, Eli O. Meltzer (2012). "Work, Classroom and Activity Impairment Instruments". In: Clinical drug investigation, 11(5), 278-288.
- QUOTE: The validity and responsiveness of allergy-specific questions in the format of the Work Productivity and Activity Impairment (WPAI) questionnaire were tested, and the work, activity and classroom impairment of allergic rhinitis patients with moderate to severe allergy symptoms were described. Allergy-specific WPAI (WPAI-AS) instruments were completed at baseline and at week 1 and week 2 by patients in 2 multicentre, double-blind, randomised placebo-controlled clinical trials of antihistamines: terfenadine (work/activity impairment; n = 422) or fexofenadine (MDL 16,455A) (classroom impairment; n = 241). The validity, responsiveness to clinical change, and reproducibility in the absence of clinical change of the WPAI-AS were measured independently by symptom severity scores. Allergy symptoms were associated with impairment at work, at other regular activities, and in the classroom. The studies established the discriminative and evaluative validity, reproducibility and responsiveness of WPAI-AS measures of work impairment, overall work impairment, activity impairment and classroom impairment secondary to allergy symptoms, but not of work or classroom time missed.
2012b
- (Reilly et al., 2012) ⇒ Margaret C. Reilly, Arthur S. Zbrozek, Ellen M. Dukes (2012). "The Validity and Reproducibility of a Work Productivity and Activity Impairment Instrument". In: PharmacoEconomics volume 4: 353–365.
- QUOTE: The construct validity of a quantitative work productivity and activity impairment (WPAI) measure of health outcomes was tested for use in clinical trials, along with its reproducibility when administered by 2 different methods. 106 employed individuals affected by a health problem were randomised to receive either 2 self-administered questionnaires (self administration) or one self-administered questionnaire followed by a telephone interview (interviewer administration). Construct validity of the WPAI measures of time missed from work, impairment of work and regular activities due to overall health and symptoms, were assessed relative to measures of general health perceptions, role (physical), role (emotional), pain, symptom severity and global measures of work and interference with regular activity.