2015 DistributeAIBenefitsFairly

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Subject Headings: Artificial Intelligence Prediction

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Artificial intelligence (AI) has astounding potential to accelerate scientific discovery in biology and medicine, and to transform health care. AI systems promise to help make sense of several new types of data: measurements from the 'omics' such as genomics, proteomics and metabolomics; electronic health records; and digital-sensor monitoring of health signs.

Clustering analyses can define new syndromes — separating diseases that were thought to be the same and unifying others that have the same underlying defects. Pattern-recognition technologies may match disease states to optimal treatments. For example, my colleagues and I are identifying groups of patients who are likely to respond to drugs that regulate the immune system on the basis of clinical and transcriptomic features.

In consultations, physicians might be able to display data from a 'virtual cohort' of patients who are similar to the one sitting next to them and use it to weigh up diagnoses, treatment options and the statistics of outcomes. They could make medical decisions interactively with such a system or use simulations to predict outcomes on the basis of the patient's data and that of the virtual cohort.

I have two concerns. First, AI technologies could exacerbate existing health-care disparities and create new ones unless they are implemented in a way that allows all patients to benefit. In the United States, for example, people without jobs experience diverse levels of care. A two-tiered system in which only special groups or those who can pay — and not the poor — receive the benefits of advanced decision-making systems would be unjust and unfair. It is the joint responsibility of the government and those who develop the technology and support the research to ensure that AI technologies are distributed equally.

Second, I worry about clinicians' ability to understand and explain the output of high-performance AI systems. Most health-care providers will not accept a complex treatment recommendation from a decision-support system without a clear description of how and why it was reached.

Unfortunately, the better the AI system, the harder it often is to explain. The features that contribute to probability-based assessments such as Bayesian analyses are straightforward to present; deep-learning networks, less so.

AI researchers who create the infrastructure and technical capabilities for these systems need to engage doctors, nurses, patients and others to understand how they will be used, and used fairly.

References

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 AuthorvolumeDate ValuetitletypejournaltitleUrldoinoteyear
2015 DistributeAIBenefitsFairlyStuart J. Russell
Manuela Veloso
Sabine Hauert
Russ B. Altman
Distribute AI Benefits Fairly