Amylosucrase Enzyme

An Amylosucrase Enzyme is an enzyme of Family 13 of the glycoside hydrolases (the alpha-amylases), although its biological function is the synthesis of amylose-like polymers from sucrose.

AKA: E.C. 2.4.1.4, Sucrose-Glucan Glucosyltransferase, Sucrose-1,4-Alpha-Glucan Glucosyltransferase.
Context:
- It Catalyzes the Synthesisof Alpha-Glucan from Sucrose.
- …
Example(s):
- Neisseria Polysaccharea http://www.uniprot.org/uniprot/Q9ZEU2
- PMID 12517860: “As expected, the ams gene encoding amylosucrase, responsible for production of amylopectin from sucrose, was detected in strain 93246 and all 13 N. polysaccharea strains but not in N. meningitidis and N. gonorrhoeae strains . These data suggest that strain 93246 is nonencapsulated N. meningitidis but has the ability to produce extracellular amylopectin from sucrose ”
See: Hexosyltransferases

References

(Wikipedia, 2009) ⇒ http://en.wikipedia.org/wiki/Amylosucrase
- In enzymology, an amylosucrase (EC 2.4.1.4) is an enzyme that catalyzes the chemical reaction
- sucrose + (1,4-alpha-D-glucosyl)n \rightleftharpoons D-fructose + (1,4-alpha-D-glucosyl)n+1
- Thus, the two substrates of this enzyme are sucrose and (1,4-alpha-D-glucosyl)n, whereas its two products are D-fructose and (1,4-alpha-D-glucosyl)n+1.
- This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase. Other names in common use include sucrose-glucan glucosyltransferase, and sucrose-1,4-alpha-glucan glucosyltransferase. This enzyme participates in starch and sucrose metabolism.
Gene Ontology http://amigo.geneontology.org/cgi-bin/amigo/term-details.cgi?term=GO:0047669&session_id=4446amigo1247242904
- Accession: GO:0047669
- Ontology: molecular function
- Synonyms
  - exact: sucrose-1,4-alpha-glucan glucosyltransferase activity
  - exact: sucrose-glucan glucosyltransferase activity
  - exact: sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity
- Definition
  - Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1). [source: EC:2.4.1.4, MetaCyc:AMYLOSUCRASE-RXN]