Cerebellum

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A Cerebellum is a Brain Structure that coordinates voluntary movements and supports functions related to balance, coordination, and posture.

  • Context:
    • It can (typically) be located underneath the Cerebral Hemispheres, at the back of the Brain.
    • It can (typically) be divided into two hemispheres, connected by a structure called the Vermis.
    • It can (typically) receive input from the Sensory Systems, the Spinal Cord, and other parts of the brain, and integrate these inputs to fine-tune motor activity.
    • It can (often) contain more than half of the brain's Neurons, despite its relatively small size.
    • It can (often) be involved in motor learning and the timing of movements.
    • It can (often) modulate the outputs of other brain systems to fine-tune motor actions, but it does not initiate movement.
    • It can (often) be affected by various diseases and conditions, such as Ataxia, which results in a lack of muscle control or coordination.
    • ...
  • Example(s):
    • a Human Cerebellum, which plays a crucial role in maintaining posture and balance, enabling smooth and coordinated muscle movements.
    • a Bird Cerebellum assist in their motor control and coordination.
    • ...
  • Counter-Example(s):
    • Cerebral Cortex, which is involved in higher brain functions such as thought, memory, and emotion.
    • Brain Stem, which controls basic life functions such as breathing and heartbeat.
  • See: Motor System, Neuroanatomy, Neuroscience, Brain, Consciousness, Cerebrum.


References

2012

  • http://en.wikipedia.org/wiki/Cerebellum
    • QUOTE: The cerebellum (Latin for little brain) is a region of the brain that plays an important role in motor control. It may also be involved in some cognitive functions such as attention and language, and in regulating fear and pleasure responses,[1] but its movement-related functions are the most solidly established. The cerebellum does not initiate movement, but it contributes to coordination, precision, and accurate timing. It receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine tune motor activity.[2] Because of this fine-tuning function, damage to the cerebellum does not cause paralysis, but instead produces disorders in fine movement, equilibrium, posture, and motor learning.

      In terms of anatomy, the cerebellum has the appearance of a separate structure attached to the bottom of the brain, tucked underneath the cerebral hemispheres. The surface of the cerebellum is covered with finely spaced parallel grooves, in striking contrast to the broad irregular convolutions of the cerebral cortex. These parallel grooves conceal the fact that the cerebellum is actually a continuous thin layer of tissue (the cerebellar cortex), tightly folded in the style of an accordion. Within this thin layer are several types of neurons with a highly regular arrangement, the most important being Purkinje cells and granule cells. This complex neural network gives rise to a massive signal-processing capability, but almost all of its output is directed to a set of small deep cerebellar nuclei lying in the interior of the cerebellum.

      In addition to its direct role in motor control, the cerebellum also is necessary for several types of motor learning, the most notable one being learning to adjust to changes in sensorimotor relationships. Several theoretical models have been developed to explain sensorimotor calibration in terms of synaptic plasticity within the cerebellum. Most of them derive from early models formulated by David Marr and James Albus, which were motivated by the observation that each cerebellar Purkinje cell receives two dramatically different types of input: On one hand, thousands of inputs from parallel fibers, each individually very weak; on the other hand, input from one single climbing fiber, which is, however, so strong that a single climbing fiber action potential will reliably cause a target Purkinje cell to fire a burst of action potentials. The basic concept of the Marr-Albus theory is that the climbing fiber serves as a "teaching signal", which induces a long-lasting change in the strength of synchronously activated parallel fiber inputs. Observations of long-term depression in parallel fiber inputs have provided support for theories of this type, but their validity remains controversial.

  1. Wolf U, Rapoport MJ, Schweizer TA (2009). "Evaluating the affective component of the cerebellar cognitive affective syndrome". J. Neuropsychiatry Clin. Neurosci. 21 (3): 245–53. doi:10.1176/appi.neuropsych.21.3.245. PMID 19776302. 
  2. Fine EJ, Ionita CC, Lohr L (2002). "The history of the development of the cerebellar examination". Semin Neurol 22 (4): 375–84. doi:10.1055/s-2002-36759. PMID 12539058.