Patient Diary
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A Patient Diary is a tool used during a clinical trial or a disease treatment to assess the patient's condition (e.g. symptom severity, quality of life) or to measure treatment compliance.
- Context:
- It can range from being a Empty Diary to being a Partially-Completed Diary to being a Completed Diary.
- It can range from being a Paper Patient Diary to being a Electronic Patient Diary.
- …
- Example(s):
- See: Patient Reported Outcome.
References
2022
- (Wikipedia, 2022) ⇒ https://en.wikipedia.org/wiki/Patient_diary Retrieved:2022-9-15.
- A patient diary is a tool used during a clinical trial or a disease treatment to assess the patient's condition (e.g. symptom severity, quality of life) or to measure treatment compliance. An electronic patient diary registers the data in a storage device and allows for automatically monitoring the time the entry was made.
Frequent recording of symptoms using a diary helps to reduce recall bias. Electronic diaries ensure entries are made as scheduled, and not, for example, in a batch immediately before the clinic visit.
Patient diaries are also way to find out if a patient takes the medication according to the treatment schedule, which is an important problem during clinical trials and the treatment of degenerative diseases with relatively few symptoms.
- A patient diary is a tool used during a clinical trial or a disease treatment to assess the patient's condition (e.g. symptom severity, quality of life) or to measure treatment compliance. An electronic patient diary registers the data in a storage device and allows for automatically monitoring the time the entry was made.
2022
- (Löhle et al., 2022) ⇒ Matthias Löhle, Alexander Bremer, Florin Gandor, Jonathan Timpka, Per Odin, Georg Ebersbach, and Alexander Storch. (2022). “Validation of the PD Home Diary for Assessment of Motor Fluctuations in Advanced Parkinson’s Disease.” In: Nature npj Parkinson's Disease, 8(1).
- QUOTE: ... The Parkinson’s disease (PD) home diary is frequently used in clinical trials to measure efficacy of medical treatments for motor fluctuations in advanced PD. This prospective study in fluctuating PD patients examines the validity of the diary for quantification of motor states in comparison to direct clinical observation.
2012
- (Papapetropoulos, 2012) ⇒ Spyridon Papapetropoulos. (2012). “Patient Diaries As a Clinical Endpoint in Parkinson's Disease Clinical Trials.” CNS Neuroscience & Therapeutics, 18(5).
- QUOTE: ... Reduced compliance, recall bias and diary fatigue are common problems seen with patient diary reported measures. Electronic diaries may help reducing some of these problems but may be associated with other challenges in large, multicenter studies. ...
2012
- (Papapetropoulos, 2012) ⇒ Spyridon Papapetropoulos. (2012). “Patient Diaries As a Clinical Endpoint in Parkinson's Disease Clinical Trials.” CNS neuroscience & therapeutics 18, no. 5
1999
- (Henegouwen et al., 1999) ⇒ M. T. H. van Berge Henegouwen, and H. F . Van Driel. (1999). “A Patient Diary As a Tool to Improve Medicine Compliance.” In: Pharmacy World and Science, 21(1).
- ABSTRACT: Compliance is a well recognised but still unresolved health problem; improvement of compliance to treatment would increase cost‐effectiveness. One of the current methods used to measure treatment compliance in a clinical drug trial is through the use of a patient diary. In order to interpret data in these diaries it is important to also assess how compliant patients are in completing diaries. Patient compliance of standard diary completion was measured in 69 patients with perennial rhinitis, who were randomised into a double blind, placebo controlled trial with a new corticosteroid drug. During 3 months the patients were instructed to complete a diary twice a day for the following parameters: rhinitis signs and symptoms, dosage times, concomitant medication, use of rescue medication and comments. Diaries were reviewed by the physician at scheduled visits. Twenty patients (30%) completed their diaries for all items perfectly, while 62 patients (94%) completed more than 95% of all items. The compliance of diary completion in a well controlled trial is high. Overall completion of the diary was not influenced by age, gender, race, use of concomitant medication or treatment failure. Significant correlations were found for study duration and physician. This study suggests that completion of a daily diary is positively correlated with patient compliance in medication intake. Physicians could consider using diaries to try to improve compliance. More explicit investigations are needed.