Urease
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A Urease is an enzyme that Catalyzes the Hydrolysis of Urea to form Ammonium Carbonate.
- Context:
- It can cleave Phospholipids (just before the Phosphate Group).
- Example(s):
- Helicobacter pylori http://www.uniprot.org/uniprot/P14916
- PMID 1348725: “Helicobacter pylori urease is an extracellular, cell-bound enzyme with a molecular weight of approximately 600,000 (600K enzyme) comprising six 66K and six 31K subunits. ”
- See: Helicobacter Pylori, Enteric Bacteria.
References
2009
- (Wikipedia, 2009) ⇒ http://en.wikipedia.org/wiki/Urease
- Urease (EC 3.5.1.5) is an enzyme that catalyzes the hydrolysis of urea into carbon dioxide and ammonia. The reaction occurs as follows:
- (NH2)2CO + H2O → CO2 + 2NH3
- In 1926 James Sumner showed that urease is a protein. Urease is found in bacteria, yeast and several higher plants.
- Urease (EC 3.5.1.5) is an enzyme that catalyzes the hydrolysis of urea into carbon dioxide and ammonia. The reaction occurs as follows:
- Gene Ontology http://amigo.geneontology.org/cgi-bin/amigo/term-details.cgi?term=GO:0009039&session_id=4594amigo1245235139
- Accession: GO:0009039
- Ontology: molecular function
- Synonyms
- exact: urea amidohydrolase activity
- Definition
- Catalysis of the reaction: urea + H2O = CO2 + 2 NH3. [source: EC:3.5.1.5]