Coding Symbols for Thesaurus of Adverse Reaction Terms (COSTART)
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A Coding Symbols for Thesaurus of Adverse Reaction Terms (COSTART) is a Medical Coding Dictionary that can be used for coding, filing, and retrieving post-marketing adverse drug and biologic experience reports.
- AKA: COSTART Medical Dictionary.
- Context:
- Website: http://hedwig.mgh.harvard.edu/biostatistics/files/costart.html (obsolete)
- It has been developed by the U.S. Food and Drug Administration (FDA).
- It has been replaced by the MedDRA Dictionary.
- Example(s):
- …
- Counter-Example(s):
- See: Clinical Terminology Standard, Medical Database, Medical Ontology, Clinical Research Glossary, Clinical Data Standard, Medical Classification System, Adverse Reaction, Adverse Effect, Medical Treatment, Medical Diagnosis, Clinical Trial.
References
2022a
- (BioPortal, 2022) ⇒ https://bioportal.bioontology.org/ontologies/COSTART Retrieved:2022-03-13.
- QUOTE: Coding Symbols for Thesaurus of Adverse Reaction Terms (COSTART). 5th ed. Rockville (MD). COSTART is used for coding, filing, and retrieving post-marketing adverse drug and biologic experience reports. COSTART is organized in body system and pathophysiology hierarchies, as well as a separate fetal/neonatal category of less than 20 terms. COSTART has been superseded by the Medical Dictionary for Regulatory Activities (MedDRA) Terminology. For more information about MedDRA in the Metathesaurus, see the MedDRA source synopsis. COSTART was last updated in the Metathesaurus in 1999.
2022b
- (NIH-NLM, 2022) ⇒ https://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/CST/index.html Retrieved:2022-03-13.
- QUOTE: The Coding Symbols for a Thesaurus of Adverse Reaction Terms (COSTART) was developed by the U.S. Food and Drug Administration (FDA).
Purpose
COSTART is used for coding, filing, and retrieving post-marketing adverse drug and biologic experience reports.
Description
COSTART is organized in body system and pathophysiology hierarchies, as well as a separate fetal/neonatal category of less than 20 terms.
COSTART has been superseded by the Medical Dictionary for Regulatory Activities (MedDRA) Terminology. For more information about MedDRA in the Metathesaurus, see the MedDRA source synopsis.
- QUOTE: The Coding Symbols for a Thesaurus of Adverse Reaction Terms (COSTART) was developed by the U.S. Food and Drug Administration (FDA).
2022c
- (Wkipedia, 2022) ⇒ https://en.wikipedia.org/wiki/COSTART Retrieved:2022-03-13.
- QUOTE: The Coding Symbols for a Thesaurus of Adverse Reaction Terms (COSTART) was developed by the United States Food and Drug Administration (FDA) for the coding, filing and retrieving of post-marketing adverse reaction reports.[1] COSTART provides a method to deal with the variation in vocabulary used by those who submit adverse event reports to the FDA. Use of this dictionary allowed for standardization of adverse reaction reporting towards the FDA in a consistent way.
COSTART was last updated in 1999. It has been replaced by the Medical Dictionary for Regulatory Activities, MedDRA.
- QUOTE: The Coding Symbols for a Thesaurus of Adverse Reaction Terms (COSTART) was developed by the United States Food and Drug Administration (FDA) for the coding, filing and retrieving of post-marketing adverse reaction reports.[1] COSTART provides a method to deal with the variation in vocabulary used by those who submit adverse event reports to the FDA. Use of this dictionary allowed for standardization of adverse reaction reporting towards the FDA in a consistent way.
- ↑ "Coding Symbols for Thesaurus of Adverse Reaction Terms (COSTART) Source Information". Unified Medical Language System® (UMLS®). U.S. National Library of Medicine. 23 November 2010. Retrieved 29 June 2015.
2010
- (Babre. 2010) ⇒ Deven Babre (2010). "Medical Coding in Clinical Trials". In: Perspectives in clinical research, 1(1), 29.
- QUOTE: There are several standardized medical coding dictionaries in the market; however five dictionaries listed below are used for coding:
- COSTART - Coding Symbols for Thesaurus of Adverse Reaction Terms
- ICD9CM - International Classification of Diseases 9 Revision Clinical Modification
- MedDRA - Medical Dictionary for Regulatory Activities
- WHO-ART - World Health Organisation Adverse Reac-tions Terminology
- WHO-DDE - World Health Organisation Drug Dictio-nary Enhanced
- QUOTE: There are several standardized medical coding dictionaries in the market; however five dictionaries listed below are used for coding:
- Out of the above five, two widely used medical coding dictionaries used for coding medical terms generated in clinical trials are MedDRA and WHO-DDE. To maintain uniformity in reporting a term is next to impossible in any given clinical trial. However for a coder it is a challenging task to ensure that the term recorded/reported on data collection instrument (CRF/eCRF) is coded appropriately.