Munich Information Center for Protein Sequences

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The Munich Information Center for Protein Sequences is a Genomics Database.

References

  • http://mips.gsf.de/
    • The Institute of Bioinformatics and Systems Biology (IBI) is part of the HZM - German Research Center for Environmental Health and hosts the Munich Information Center for Protein Sequences (MIPS). Its main focus is the genome-oriented bioinformatics, in particular the systematic analysis of genome information including the development and application of bioinformatics methods in genome annotation, expression analysis and proteomics. MIPS supports and maintains a set of generic databases as well as the systematic comparative analysis of microbial, fungal, and plant genomes.
  • (Wikipedia, 2009) ⇒ http://en.wikipedia.org/wiki/Munich_Information_Center_for_Protein_Sequences
    • The Munich Information Center for Protein Sequences (MIPS) is a research center hosted at the Institute for Bioinformatics (IBI) at Neuherberg, Germany with a focus on genome oriented bioinformatics, in particular on the systematic analysis of genome information including the development and application of bioinformatics methods in genome annotation, gene expression analysis and proteomics. MIPS supports and maintains a set of generic databases as well as the systematic comparative analysis of microbial, fungal, and plant genomes.

2009

  • (Cusick et al., 2009) ⇒ Michael E Cusick, Haiyuan Yu, Alex Smolyar, Kavitha Venkatesan, Anne-Ruxandra Carvunis, Nicolas Simonis, Jean-François Rual, Heather Borick, Pascal Braun, Matija Dreze, Jean Vandenhaute, Mary Galli, Junshi Yazaki, David E Hill, Joseph R Ecker, Frederick P Roth, and Marc Vidal. (2009). “Literature-Curated Protein Interaction Datasets.” In: Nature Methods 6, 39 - 46 (2009)
    • Manual curation of protein interactions from literature began with pioneering curation for the yeast Saccharomyces cerevisiae by the Yeast Proteome Database (YPD)13. Those early efforts demonstrated that effective curation was possible and also broadly aimed to capture all types of functional and genomic information, not only PPIs. Genomic databases dedicated to a single model organism arose in parallel with genome sequencingprojects, for example, the Saccharomyces Genome Database (SGD)14 and The Arabidopsis Information Resource (TAIR)15. Although initially devoted to sequence information, many of these databases eventually added many types of literature-curated information, including PPI data. In time, the publications reporting PPIs exceeded the capacity of specialized genome databases and led to the creation of databases dedicated to PPIs, for example, the Munich Information Center for Protein Sequence (MIPS) protein interaction database16, the Biomolecular Interaction Network Database (BIND)17, the Database of Interacting Proteins (DIP)18, the Molecular Interaction database (MINT)19 and the protein Interaction database (IntAct)20. More recent PPI curation efforts, the Biological General Repository for Interaction Datasets (BioGRID)21 and the Human Protein Reference Database (HPRD)22, have attempted larger-scale curation of data from more manuscripts and more interactions.

2005

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