Centralized Clinical Trial (CCT)

A Centralized Clinical Trial (CCT) is a clinical trial process that coordinates patient data collection and trial management through a central research facility.

• AKA: Centralized Clinical Trial, Centralized Randomized Clinical Trial.
• Context:
  • It can typically require patients to travel to designated research sites for trial participation.
  • It can maintain standardized protocols through centralized oversight and quality control.
  • It can support data integrity through unified data collection systems.
  • It can range from being a Single-Site Clinical Trial to being a Multi-Site Centralized Trial, depending on its trial scope.
  • It can facilitate regulatory compliance through centralized documentation.

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• Examples:

Traditional Clinical Trials, such as:

• Phase III Cancer Drug Trial with on-site patient monitoring.
  • • Cardiovascular Treatment Study for controlled environment testing.

Hospital-Based Trials, such as:

• • • Academic Medical Center Trial in specialized research unit.
• Teaching Hospital Study with standardized protocol implementation.
  • ...
• Counter-Examples:

Decentralized Clinical Trial, which enables remote patient participation. Hybrid Clinical Trial, which combines centralized and remote approaches.

• • Virtual Clinical Trial, which operates entirely through digital platforms.
• See: Clinical Trial Management System, Research Site Selection, Centralized Data Management, Clinical Trial Protocol., COVID-19, Association of Clinical Research Organizations (ACRO), Clinical Trials Transformation Initiative (CTTI), Decentralization, Decentralized System, Decentralized Web, Decentralized Computing, Decentralized Research, Randomized Clinical Trial, Contract Research Organization (CRO), Telehealth, Digital Medicine, Telemedicine

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